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1

Fluoroquinolone antibacterials: SAR, mechanism of action, resistance, and clinical aspects

Thomas D. Gootz, Katherine E. Brighty

Journal:

Medicinal Research Reviews

Year:

1996

Language:

english

File:

PDF, 3.31 MB

english, 1996

2

Ash and slag properties for co-gasification of sewage sludge and coal: An experimentally validated modeling approach

Schwitalla, Daniel, Reinmöller, Markus, Forman, Clemens, Wolfersdorf, Christian, Gootz, Matthias, Bai, Jin, Guhl, Stefan, Neuroth, Markus, Meyer, Bernd

Journal:

Fuel Processing Technology

Year:

2018

Language:

english

File:

PDF, 790 KB

english, 2018

3

Competition of different scattering channels in electron impact vibrational excitation of thin solid films of sulfur hexafluoride

B. Göötz, E. Burean, P. Swiderek

Journal:

Surface Science

Year:

2005

Language:

english

File:

PDF, 445 KB

english, 2005

4

CO 2 -to-X and Coal-to-X Concepts in Pulverized Coal Combustion Power Plants

Wolfersdorf, Christian, Forman, Clemens, Keller, Florian, Gootz, Matthias, Meyer, Bernd

Journal:

Energy Procedia

Year:

2017

Language:

english

File:

PDF, 361 KB

english, 2017

5

Über Fluor-Derivate von Kohlehydraten

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Year:

1929

Language:

german

File:

PDF, 216 KB

german, 1929

6

Über einige neue 1-Acyl-Derivate der Glucose. Synthese des α-Benzyl-glucosids

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Year:

1929

Language:

german

File:

PDF, 350 KB

german, 1929

7

Synthese eines Tetrasaccharid-acetats

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Year:

1931

Language:

german

File:

PDF, 335 KB

german, 1931

8

Synthese des Saligenin-β-d-galaktosids

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Year:

1932

Language:

german

File:

PDF, 206 KB

german, 1932

9

Electron-energy-loss spectroscopy of solid phenylacetylene

P. Swiderek, B. Göötz, H. Winterling

Journal:

Chemical Physics Letters

Year:

1998

Language:

english

File:

PDF, 110 KB

english, 1998

10

High-resolution electron-energy-loss spectroscopy of molecular multilayer film growth and properties

B. Göötz, O. Kröhl, P. Swiderek

Journal:

Journal of Electron Spectroscopy and Related Phenomena

Year:

2001

Language:

english

File:

PDF, 217 KB

english, 2001

11

Beitrag zur spätinfantilen Hallervorden-Spatzschen Krankheit

F. Seitelberger, E. Gootz, H. Gross

Journal:

Acta Neuropathologica

Year:

1963

Language:

german

File:

PDF, 2.50 MB

german, 1963

12

Zur Substruktur der Myoklonuskörper bei progressiver Myoklonusepilepsie (Typ Unverricht)

R. Schnabel, M. Gootz

Journal:

Acta Neuropathologica

Year:

1971

File:

PDF, 1.64 MB

1971

13

Methoden für neurohistologische Untersuchungen des peripheren und autonomen Nervensystems an bioptisch gewonnenem Material

M. Gootz, F. Herzog, G. Lassmann, C. Reichert

Journal:

Acta Neuropathologica

Year:

1974

Language:

german

File:

PDF, 269 KB

german, 1974

14

Atypical inclusion bodies with myoclonic epilepsy

D. K. Dastur, B. S. Singhal, M. Gootz, F. Seitelberger

Journal:

Acta Neuropathologica

Year:

1966

Language:

english

File:

PDF, 1.76 MB

english, 1966

15

Bacteriological activity of trovafloxacin, a new quinolone, against respiratory tract pathogens

J. -C. Pechère, T. D. Gootz

Journal:

European Journal of Clinical Microbiology & Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 860 KB

english, 1998

16

Vibrational excitation by electron impact in thin solid films of cyclopropane

B. Göötz, H. Winterling, P. Swiderek

Journal:

Journal of Electron Spectroscopy and Related Phenomena

Year:

1999

Language:

english

File:

PDF, 311 KB

english, 1999

17

The low-lying singlet-triplet transitions of phenylacetylene and styrene: Analysis of the vibronic structure

Petra Swiderek, Britta Göötz

Journal:

Berichte der Bunsengesellschaft für physikalische Chemie

Year:

1998

Language:

english

File:

PDF, 974 KB

english, 1998

18

ChemInform Abstract: Fluoroquinolone Antibacterials: SAR, Mechanism of Action, Resistance, and Clinical Aspects

T. D. GOOTZ, K. E. BRIGHTY

Journal:

Year:

1996

File:

PDF, 25 KB

1996

19

The forgotten Gram-negative bacilli: What genetic determinants are telling us about the spread of antibiotic resistance

Thomas D. Gootz

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 268 KB

english, 2006

20

Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone

Krisztina M. Papp-Wallace, Christopher R. Bethel, Thomas D. Gootz, Wenchi Shang, Justin Stroh, William Lau, Dale McLeod, Loren Price, Anthony Marfat, Anne Distler, Sarah M. Drawz, Hansong Chen, Emily

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

21

Enterococcal virulence determinants may be involved in resistance to clinical therapy

Andrea Marra, Fadia Dib-Hajj, Lucinda Lamb, Frank Kaczmarek, Wenchi Shang, Gretchen Beckius, Anthony J. Milici, Ivette Medina, Thomas D. Gootz

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2007

Language:

english

File:

PDF, 338 KB

english, 2007

22

In vitro activity of CP-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial

Thomas D. Gootz, Katherine E. Brighty, Marge R. Anderson, Brenda J. Schmieder, Suzanne L. Haskell, Joyce A. Sutcliffe, Michael J. Castaldi, Paul R. McGuirk

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

1994

Language:

english

File:

PDF, 708 KB

english, 1994

23

Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation

James M. Harrington, Tom Gootz, Mark Flanagan, Majinder Lall, John O’Donnell, Jennifer Winton, John Mueller, Alvin L. Crumbliss

Journal:

Year:

2012

Language:

english

File:

PDF, 574 KB

english, 2012

24

O496 Multiresistant Klebsiella pneumoniae from NYC hospitals contain β-lactamase KPC-2 or KPC-3 and porin changes

T. Gootz, F. Dib-Hajj, M. Lescoe, R. Huard, P. Della Latta

Journal:

International Journal of Antimicrobial Agents

Year:

2007

Language:

english

File:

PDF, 72 KB

english, 2007

25

Acinetobacter baumannii: an emerging multidrug-resistant threat

Gootz, Thomas D, Marra, Andrea

Journal:

Expert Review of Anti-infective Therapy

Year:

2008

Language:

english

File:

PDF, 396 KB

english, 2008

26

Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine

McGuirk, Paul R., Jefson, Martin R., Mann, Douglas D., Elliott, Nancy C., Chang, Polly, Cisek, Eugene P., Cornell, C. Peter, Gootz, Thomas D., Haskell, Susan L.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.22 MB

english, 1992

27

Activity of Trovafloxacin Against Topoisomerases and GyrA/Gr1A Mutants ofStaphylococcus aureus

Dr Thomas D. Gootz, Richard P. Zaniewski, Suzanne L. Haskell, Frank S. Kaczmarek…

Journal:

Year:

1999

Language:

english

File:

PDF, 148 KB

english, 1999

28

Global dissemination of β2-lactamases mediating resistance to cephalosporins and carbapenems

Gootz, Thomas D

Journal:

Expert Review of Anti-infective Therapy

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

29

Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with an extended half-life and excellent tissue distribution.

Girard, A E, Girard, D, English, A R, Gootz, T D, Cimochowski, C R, Faiella, J A, Haskell, S L, Retsema, J A

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1987

Language:

english

File:

PDF, 1.56 MB

english, 1987

30

Action of Quinolones against Staphylococcus aureus Topoisomerase IV: Basis for DNA Cleavage Enhancement †

Anderson, Virginia E., Zaniewski, Richard P., Kaczmarek, Frank S., Gootz, Thomas D., Osheroff, Neil

Journal:

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

31

Depth and Angular Profiles of Inelastic Low-Energy Electron Scattering in Condensed Molecular Samples

Göötz, Britta, Popović, Duška B., David, Donald E., Michl, Josef, Swiderek, Petra

Journal:

Journal of Physical Chemistry B

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

32

The chemistry and biological profile of trovafloxacin

Brighty, K. E., Gootz, T. D.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

1997

Language:

english

File:

PDF, 188 KB

english, 1997

33

Resistance to Cefamandole: Derepression of β-Lactamases by Cefoxitin and Mutation in Enterobacter cloacae

Thomas D. Gootz, Christine C. Sanders and Richard V. Goering

Journal:

The Journal of Infectious Diseases

Year:

1982

Language:

english

File:

PDF, 1.46 MB

english, 1982

34

Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents.

Barrett, J F, Gootz, T D, McGuirk, P R, Farrell, C A, Sokolowski, S A

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1989

Language:

english

File:

PDF, 2.42 MB

english, 1989

35

In vitro activity of CP-65,207, a new penem antimicrobial agent, in comparison with those of other agents.

Gootz, T, Retsema, J, Girard, A, Hamanaka, E, Anderson, M, Sokolowski, S

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1989

Language:

english

File:

PDF, 1.17 MB

english, 1989

36

Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus

Kaczmarek, F. S., Zaniewski, R. P., Gootz, T. D., Danley, D. E., Mansour, M. N., Griffor, M., Kamath, A. V., Cronan, M., Mueller, J., Sun, D., Martin, P. K., Benton, B., McDowell, L., Biek, D., Schmid

Journal:

Journal of Bacteriology

Year:

2001

Language:

english

File:

PDF, 777 KB

english, 2001

37

Genetic and Molecular Characterization of -Lactamase-Negative Ampicillin-Resistant Haemophilus influenzae with Unusually High Resistance to Ampicillin

Kaczmarek, F. S., Gootz, T. D., Dib-Hajj, F., Shang, W., Hallowell, S., Cronan, M.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2004

Language:

english

File:

PDF, 136 KB

english, 2004

38

Genetic Organization of Transposase Regions Surrounding blaKPC Carbapenemase Genes on Plasmids from Klebsiella Strains Isolated in a New York City Hospital

Gootz, T. D., Lescoe, M. K., Dib-Hajj, F., Dougherty, B. A., He, W., Della-Latta, P., Huard, R. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 487 KB

english, 2009

39

Placement of alkyl substituents on the C-7 piperazine ring of fluoroquinolones: dramatic differential effects on mammalian topoisomerase II and DNA gyrase.

Gootz, T D, McGuirk, P R, Moynihan, M S, Haskell, S L

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1994

Language:

english

File:

PDF, 624 KB

english, 1994

40

In vitro assays used to measure the activity of topoisomerases.

Barrett, J F, Sutcliffe, J A, Gootz, T D

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1990

Language:

english

File:

PDF, 1.85 MB

english, 1990

41

Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential.

Elsea, S H, McGuirk, P R, Gootz, T D, Moynihan, M, Osheroff, N

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1993

Language:

english

File:

PDF, 1.49 MB

english, 1993

42

Development of resistance to cephalosporins in clinical strains of Citrobacter spp.

Gootz, T D, Jackson, D B, Sherris, J C

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1984

Language:

english

File:

PDF, 960 KB

english, 1984

43

Inhibitory effects of quinolone antibacterial agents on eucaryotic topoisomerases and related test systems.

Gootz, T D, Barrett, J F, Sutcliffe, J A

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1990

Language:

english

File:

PDF, 1008 KB

english, 1990

44

Pharmacokinetic studies of CP-74,667, a new quinolone, in laboratory animals.

Girard, D, Gootz, T D, McGuirk, P R

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1992

Language:

english

File:

PDF, 1.13 MB

english, 1992

45

Comparison of three DNA hybridization methods for detection of the aminoglycoside 2"-O-adenylyltransferase gene in clinical bacterial isolates.

Gootz, T D, Tenover, F C, Young, S A, Gordon, K P, Plorde, J J

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1985

Language:

english

File:

PDF, 1.40 MB

english, 1985

46

Characterization of beta-lactamase induction in Enterobacter cloacae.

Gootz, T D, Sanders, C C

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1983

Language:

english

File:

PDF, 1.03 MB

english, 1983

47

Biochemical characteristics and physiological significance of major DNA topoisomerases.

Sutcliffe, J A, Gootz, T D, Barrett, J F

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1989

Language:

english

File:

PDF, 1.56 MB

english, 1989

48

The current state of antibacterial research

Gootz, Thomas D

Journal:

Expert Review of Anti-infective Therapy

Year:

2003

Language:

english

File:

PDF, 52 KB

english, 2003

49

Development of two DNA probes for differentiating the structural genes of subclasses I and II of the aminoglycoside-modifying enzyme 3'-aminoglycoside phosphotransferase.

Young, S A, Tenover, F C, Gootz, T D, Gordon, K P, Plorde, J J

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1985

Language:

english

File:

PDF, 1.23 MB

english, 1985

50

The Spread of Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae to Upstate New York

Lomaestro, Ben M., Tobin, Ellis H., Shang, Wenchi, Gootz, Thomas

Journal:

Clinical Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 66 KB

english, 2006

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